Uncovered Insights On Establishing Details For Qualification For Medicine


If the findings by the Duke-led team bear out in human studies, the drug could become the first treatment option for Prader-Willi syndrome. The concept proven in this study could also apply immediately to other similar type of genomic imprinting disorders in which children only inherit an active copy of a gene from one parent. “Our findings are promising and indicate that we may have a path forward for the first time to treat the severe, life-limiting features of this genetic disorder,” said Yong-hui Jiang, M.D., Ph.D., associate professor in Duke’s departments of Pediatrics and Neurobiology. Jiang is senior author of a study published online Dec. 26 in the journal Nature Medicine. In most cases of Prader-Willi syndrome, the responsible gene in the region of chromosome 15 from the father is missing and the mother’s copy is silent. Jiang and colleagues focused their work on finding a way to activate the silent gene from the mother’s chromosome to recover the necessary gene function that would ordinarily be performed by the father’s gene. The researchers — including Bryan Roth, M.D., Ph.D, at the University of North Carolina at Chapel Hill and co-first authors Yuna Kim, Ph.D., and Hyeong-min Lee, Ph.D. — conducted screenings of more than 9,000 compounds. informative postUsing fluorescent marker in mouse embryonic fibroblasts, the researchers were able to see whether any of the small molecules triggered the cells to glow, which indicated they were capable of activating the maternal copy of the Prader-Willi gene.

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In private placements in May and September, 2016, the Company issued an aggregate of 2,608,910 warrants to purchase common stock. The warrants have an exercise price of $2.25 per share, are exercisable six months from the date of issuance, and expire five years from the initial exercise date. The Company will not receive proceeds from any resale of these shares; but, would receive the exercise price if and when any warrants are exercised. This press release refers to warrants previously purchased, and shall not constitute an offer to sell, or the solicitation of an offer to buy, any of the securities described herein. There shall not be any offer, solicitation of an offer to buy, or sale of securities in any state or jurisdiction in which such an offering, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. A registration statement relating to these securities has been filed with the Securities and Exchange Commission but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. practical concepts for quick programs of medical school interview helpA copy of a written prospectus for these securities may be obtained by contacting Cancer Genetics, Inc., 201 Rt. 17N, Suite 201, Rutherford, NJ 07070 Att: Corporate Secretary. About Cancer Genetics: Cancer Genetics, Inc. is an emerging leader in enabling precision medicine for oncology through the use of molecular markers and information.CGI is developing a global footprint with locations in the US, India and China. We have established strong clinical research collaborations with major cancer centers such as Memorial Sloan Kettering, The Cleveland Clinic, Mayo Clinic, Keck School of Medicine at USC and the National Cancer Institute. The Company offers a comprehensive range of laboratory services that provide critical genomic and biomarker information. Its state-of-the-art reference labs are CLIA-certified and CAP-accredited in the US and have licensure from several states including New York State.

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